![]() ![]() The review also showed that the testing methods used in adrenal fatigue studies were unable to determine adrenal function.The review, succinctly titled “Adrenal fatigue does not exist,” looked at 58 different studies and found no evidence to support a meaningful connection between fatigue and cortisol levels or patterns. A 2016 systematic review concluded that there was no proof of the existence of adrenal fatigue.However, high-quality research simply has not been able to prove that adrenal fatigue is real. Eventually, this renders them unable to produce sufficient cortisol. The theory behind adrenal fatigue is essentially that with prolonged or chronic stress exposure, the adrenal glands become overworked and overtired. The adrenal glands are responsible for several hormonal functions, including releasing cortisol in response to stress. ![]()
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